BDBM142398 US8927738, 8-Ethyl-5-methyl-2-[2-(1-methyl-2-phenyl-1H-imidazol-4-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES: CCc1ccc(C)n2nc(CCc3cn(C)c(n3)-c3ccccc3)nc12

InChI Key: InChIKey=QLKLZWAIXKNMDN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM142398 (US8927738, 8-Ethyl-5-methyl-2-[2-(1-methyl-2-pheny...) Show SMILES CCc1ccc(C)n2nc(CCc3cn(C)c(n3)-c3ccccc3)nc12 Show InChI InChI=1S/C21H23N5/c1-4-16-11-10-15(2)26-21(16)23-19(24-26)13-12-18-14-25(3)20(22-18)17-8-6-5-7-9-17/h5-11,14H,4,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US8927738 (2015) BindingDB Entry DOI: 10.7270/Q2183571
					More data for this Ligand-Target Pair