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SMILES: Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(N)c2C(N)=O)c1

InChI Key: InChIKey=AEERMDZPXWNANY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144611 (US8969583, 69) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(N)c2C(N)=O)c1 Show InChI InChI=1S/C18H16FN5O2S/c1-9-2-7-12(19)13(8-9)23-18(26)22-11-5-3-10(4-6-11)15-14(17(21)25)16(20)24-27-15/h2-8H,1H3,(H2,20,24)(H2,21,25)(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144611 (US8969583, 69) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2snc(N)c2C(N)=O)c1 Show InChI InChI=1S/C18H16FN5O2S/c1-9-2-7-12(19)13(8-9)23-18(26)22-11-5-3-10(4-6-11)15-14(17(21)25)16(20)24-27-15/h2-8H,1H3,(H2,20,24)(H2,21,25)(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair