BDBM147329 US8957093, 161

SMILES: COc1cccc(c1)[C@@H](C)NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3)c(C)c(C)c2c1

InChI Key: InChIKey=PRULFENHLQUAKX-HSZRJFAPSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM147329 (US8957093, 161) Show SMILES COc1cccc(c1)[C@@H](C)NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3)c(C)c(C)c2c1 |r| Show InChI InChI=1S/C33H32N2O2/c1-22-24(3)35(21-25-13-15-27(16-14-25)26-9-6-5-7-10-26)32-18-17-29(20-31(22)32)33(36)34-23(2)28-11-8-12-30(19-28)37-4/h5-20,23H,21H2,1-4H3,(H,34,36)/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute US Patent					Assay Description The assay was performed according to manufacturer protocol. A mixture of nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan-PPAR Green, and s...				US Patent US8957093 (2015) BindingDB Entry DOI: 10.7270/Q2X63KNR
					More data for this Ligand-Target Pair