BDBM14873 1-(2,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}phenyl)phenyl]methyl}urea::5-azaindole analog 11

SMILES: Oc1c(cccc1-c1cccc(CNC(=O)Nc2ccc(F)cc2F)c1)-c1cc2cnccc2[nH]1

InChI Key: InChIKey=IWZGRQBQDGPLFT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14873   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM14873 (1-(2,4-difluorophenyl)-3-{[3-(2-hydroxy-3-{1H-pyrr...) Show SMILES Oc1c(cccc1-c1cccc(CNC(=O)Nc2ccc(F)cc2F)c1)-c1cc2cnccc2[nH]1 Show InChI InChI=1S/C27H20F2N4O2/c28-19-7-8-24(22(29)13-19)33-27(35)31-14-16-3-1-4-17(11-16)20-5-2-6-21(26(20)34)25-12-18-15-30-10-9-23(18)32-25/h1-13,15,32,34H,14H2,(H2,31,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	-9.45	n/a	n/a	n/a	n/a	n/a	7.4	22
Celera					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				Bioorg Med Chem Lett 16: 3197-200 (2006) Article DOI: 10.1016/j.bmcl.2006.03.049 BindingDB Entry DOI: 10.7270/Q20P0X9Q
					More data for this Ligand-Target Pair