null

SMILES: COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC1CC1

InChI Key: InChIKey=KDYPRCOMAPJCET-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151316 (US8987314, B114) Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C25H30N4O7S3/c1-36-12-10-27-23(30)18-6-4-17(5-7-18)19-8-9-20-21(14-19)37-25(29-20)22(38(32,33)15-16-2-3-16)24(31)28-11-13-39(26,34)35/h4-9,14,16,22H,2-3,10-13,15H2,1H3,(H,27,30)(H,28,31)(H2,26,34,35)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	119	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151316 (US8987314, B114) Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC1CC1 Show InChI InChI=1S/C25H30N4O7S3/c1-36-12-10-27-23(30)18-6-4-17(5-7-18)19-8-9-20-21(14-19)37-25(29-20)22(38(32,33)15-16-2-3-16)24(31)28-11-13-39(26,34)35/h4-9,14,16,22H,2-3,10-13,15H2,1H3,(H,27,30)(H,28,31)(H2,26,34,35)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair