BDBM151568 US8987314, B379

SMILES: CC(=O)Nc1cccc(c1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O

InChI Key: InChIKey=ZPUQKDZSPUYPSK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151568 (US8987314, B379) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O Show InChI InChI=1S/C20H22N4O6S3/c1-12(25)23-15-5-3-4-13(10-15)14-6-7-17-16(11-14)24-20(31-17)18(32(2,27)28)19(26)22-8-9-33(21,29)30/h3-7,10-11,18H,8-9H2,1-2H3,(H,22,26)(H,23,25)(H2,21,29,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	83.7	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151568 (US8987314, B379) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O Show InChI InChI=1S/C20H22N4O6S3/c1-12(25)23-15-5-3-4-13(10-15)14-6-7-17-16(11-14)24-20(31-17)18(32(2,27)28)19(26)22-8-9-33(21,29)30/h3-7,10-11,18H,8-9H2,1-2H3,(H,22,26)(H,23,25)(H2,21,29,30)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair