BDBM152757 [(E)-[2-(pyridin-3-yl)ethylidene]amino]thiourea (3b)

SMILES: NC(=S)N\N=C\Cc1cccnc1

InChI Key: InChIKey=MBXUUEOPBQVIGU-VZUCSPMQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease [D459Y,K653P] (Canavalia ensiformis (Jack bean))	BDBM152757 ([(E)-[2-(pyridin-3-yl)ethylidene]amino]thiourea (3...) Show SMILES NC(=S)N\N=C\Cc1cccnc1 Show InChI InChI=1S/C8H10N4S/c9-8(13)12-11-5-3-7-2-1-4-10-6-7/h1-2,4-6H,3H2,(H3,9,12,13)/b11-5+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	8.2	n/a
Quaid-I-Azam University					Assay Description Urease inhibition activity was determined by indophenol method. In brief, each 140 µL assay reaction contained 40 µL buffer (100 mM urea, 0.01 mM K2H...				Chem Biol Drug Des 85: 225-30 (2015) Article DOI: 10.1111/cbdd.12379 BindingDB Entry DOI: 10.7270/Q2P55M71
					More data for this Ligand-Target Pair