BDBM153117 US8993631, 20::US9006249, Example 9-1::US9603819, Example 9-1

SMILES: C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)n1ccc(n1)C(O)=O)C(O)=O

InChI Key: InChIKey=DQOBOCPZWNUNMH-BEFAXECRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 153117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM153117 (US8993631, 20 | US9006249, Example 9-1 | US9603819...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)n1ccc(n1)C(O)=O)C(O)=O Show InChI InChI=1S/C23H23N3O5/c1-15(21(27)28)13-19(24-23(31)26-12-11-20(25-26)22(29)30)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-12,15,19H,13-14H2,1H3,(H,24,31)(H,27,28)(H,29,30)/t15-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...				US Patent US9006249 (2015) BindingDB Entry DOI: 10.7270/Q2NV9H0R
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM153117 (US8993631, 20 | US9006249, Example 9-1 | US9603819...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)n1ccc(n1)C(O)=O)C(O)=O Show InChI InChI=1S/C23H23N3O5/c1-15(21(27)28)13-19(24-23(31)26-12-11-20(25-26)22(29)30)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-12,15,19H,13-14H2,1H3,(H,24,31)(H,27,28)(H,29,30)/t15-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The activity of a compound according to the present invention can be assessed by the following in vitro & in vivo methods and/or by the following in ...				US Patent US9603819 (2017) BindingDB Entry DOI: 10.7270/Q20V8FVV
					More data for this Ligand-Target Pair
Neutral endopeptidase (NEP) (Homo sapiens (Human))	BDBM153117 (US8993631, 20 | US9006249, Example 9-1 | US9603819...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)n1ccc(n1)C(O)=O)C(O)=O Show InChI InChI=1S/C23H23N3O5/c1-15(21(27)28)13-19(24-23(31)26-12-11-20(25-26)22(29)30)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-12,15,19H,13-14H2,1H3,(H,24,31)(H,27,28)(H,29,30)/t15-,19+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair