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BDBM153749 ROCHE screening, 67

SMILES: Fc1ccc(CCNC2=NC(=O)\C(S2)=C\c2ccc3ncccc3c2)cc1

InChI Key: InChIKey=UXZMCMNLBUGBMC-UYRXBGFRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153749   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein cereblon/Serine/threonine-protein kinase TBK1


(Homo sapiens (Human))
BDBM153749
PNG
(ROCHE screening, 67)
Show SMILES Fc1ccc(CCNC2=NC(=O)\C(S2)=C\c2ccc3ncccc3c2)cc1 |t:8|
Show InChI InChI=1S/C21H16FN3OS/c22-17-6-3-14(4-7-17)9-11-24-21-25-20(26)19(27-21)13-15-5-8-18-16(12-15)2-1-10-23-18/h1-8,10,12-13H,9,11H2,(H,24,25,26)/b19-13-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 402n/an/an/an/an/an/a



Technical University of Dortmund



Assay Description
IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...


ACS Chem Biol 10: 289-98 (2015)


Article DOI: 10.1021/cb500908d
BindingDB Entry DOI: 10.7270/Q2WH2NRB
More data for this
Ligand-Target Pair