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SMILES: Cc1cc(C)n2cc(CCc3nc(cn3C)-c3ccccc3)nc2n1

InChI Key: InChIKey=CKTXMYVIEZZKTR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156269 (US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H...) Show SMILES Cc1cc(C)n2cc(CCc3nc(cn3C)-c3ccccc3)nc2n1 Show InChI InChI=1S/C20H21N5/c1-14-11-15(2)25-12-17(22-20(25)21-14)9-10-19-23-18(13-24(19)3)16-7-5-4-6-8-16/h4-8,11-13H,9-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156269 (US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H...) Show SMILES Cc1cc(C)n2cc(CCc3nc(cn3C)-c3ccccc3)nc2n1 Show InChI InChI=1S/C20H21N5/c1-14-11-15(2)25-12-17(22-20(25)21-14)9-10-19-23-18(13-24(19)3)16-7-5-4-6-8-16/h4-8,11-13H,9-10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair