BDBM156273 US9018217, 2-(1-Benzyl-4-phenyl-1H-imidazol-2-ylsulfanylmethyl)-5,7-dimethyl-imidazo[1,2-a]pyrimidine::US9592230, 2-(1-Benzyl-4-phenyl-1H-imidazol-2-ylsulfanylmethyl)-5,7-dimethyl-imidazo[1,2-a]pyrimidine

SMILES: Cc1cc(C)n2cc(CSc3nc(cn3Cc3ccccc3)-c3ccccc3)nc2n1

InChI Key: InChIKey=LPESNOKDNKQHAO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 156273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156273 (US9018217, 2-(1-Benzyl-4-phenyl-1H-imidazol-2-ylsu...) Show SMILES Cc1cc(C)n2cc(CSc3nc(cn3Cc3ccccc3)-c3ccccc3)nc2n1 Show InChI InChI=1S/C25H23N5S/c1-18-13-19(2)30-15-22(27-24(30)26-18)17-31-25-28-23(21-11-7-4-8-12-21)16-29(25)14-20-9-5-3-6-10-20/h3-13,15-16H,14,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156273 (US9018217, 2-(1-Benzyl-4-phenyl-1H-imidazol-2-ylsu...) Show SMILES Cc1cc(C)n2cc(CSc3nc(cn3Cc3ccccc3)-c3ccccc3)nc2n1 Show InChI InChI=1S/C25H23N5S/c1-18-13-19(2)30-15-22(27-24(30)26-18)17-31-25-28-23(21-11-7-4-8-12-21)16-29(25)14-20-9-5-3-6-10-20/h3-13,15-16H,14,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair