BDBM156379 US10118915, Compound 293::US9682966, 214::US9682966, 293

SMILES: COC1CN(CCC1NC1CCCCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1

InChI Key: InChIKey=PGXSSLBJKPYNJE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM156379 (US10118915, Compound 293 | US9682966, 214 | US9682...) Show SMILES COC1CN(CCC1NC1CCCCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1 Show InChI InChI=1S/C25H33N5O2/c1-16-9-10-21-18(13-16)14-20(25-26-17(2)29-32-25)24(28-21)30-12-11-22(23(15-30)31-3)27-19-7-5-4-6-8-19/h9-10,13-14,19,22-23,27H,4-8,11-12,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute US Patent					Assay Description The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...				US Patent US9682966 (2017) BindingDB Entry DOI: 10.7270/Q2610XHQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM156379 (US10118915, Compound 293 | US9682966, 214 | US9682...) Show SMILES COC1CN(CCC1NC1CCCCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1 Show InChI InChI=1S/C25H33N5O2/c1-16-9-10-21-18(13-16)14-20(25-26-17(2)29-32-25)24(28-21)30-12-11-22(23(15-30)31-3)27-19-7-5-4-6-8-19/h9-10,13-14,19,22-23,27H,4-8,11-12,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute US Patent					Assay Description Well-known assay for kappa opioid receptor				US Patent US10118915 (2018) BindingDB Entry DOI: 10.7270/Q23J3G00
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM156379 (US10118915, Compound 293 | US9682966, 214 | US9682...) Show SMILES COC1CN(CCC1NC1CCCCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1 Show InChI InChI=1S/C25H33N5O2/c1-16-9-10-21-18(13-16)14-20(25-26-17(2)29-32-25)24(28-21)30-12-11-22(23(15-30)31-3)27-19-7-5-4-6-8-19/h9-10,13-14,19,22-23,27H,4-8,11-12,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute US Patent					Assay Description Well-known assay for kappa opioid receptor				US Patent US10118915 (2018) BindingDB Entry DOI: 10.7270/Q23J3G00
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM156379 (US10118915, Compound 293 | US9682966, 214 | US9682...) Show SMILES COC1CN(CCC1NC1CCCCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1 Show InChI InChI=1S/C25H33N5O2/c1-16-9-10-21-18(13-16)14-20(25-26-17(2)29-32-25)24(28-21)30-12-11-22(23(15-30)31-3)27-19-7-5-4-6-8-19/h9-10,13-14,19,22-23,27H,4-8,11-12,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute US Patent					Assay Description The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...				US Patent US9682966 (2017) BindingDB Entry DOI: 10.7270/Q2610XHQ
					More data for this Ligand-Target Pair