BDBM15693 1-Cyclohexyl-4-(1-((4-fluorophenyl)(phenyl)methyl)piperazine-4-carbonyl)pyrrolidin-2-one::1-cyclohexyl-4-({4-[(4-fluorophenyl)(phenyl)methyl]piperazin-1-yl}carbonyl)pyrrolidin-2-one::Pyrrolidine Carboxamide Compound p28

SMILES: Fc1ccc(cc1)C(N1CCN(CC1)C(=O)C1CN(C2CCCCC2)C(=O)C1)c1ccccc1

InChI Key: InChIKey=NGRAPHDQXMLRBS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (InhA) (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM15693 (1-Cyclohexyl-4-(1-((4-fluorophenyl)(phenyl)methyl)...) Show SMILES Fc1ccc(cc1)C(N1CCN(CC1)C(=O)C1CN(C2CCCCC2)C(=O)C1)c1ccccc1 Show InChI InChI=1S/C28H34FN3O2/c29-24-13-11-22(12-14-24)27(21-7-3-1-4-8-21)30-15-17-31(18-16-30)28(34)23-19-26(33)32(20-23)25-9-5-2-6-10-25/h1,3-4,7-8,11-14,23,25,27H,2,5-6,9-10,15-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Francisco					Assay Description The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...				J Med Chem 49: 6308-23 (2006) Article DOI: 10.1021/jm060715y BindingDB Entry DOI: 10.7270/Q2707ZP0
					More data for this Ligand-Target Pair