BDBM15950 Aminopyridine-Based Inhibitor 30::N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-morpholin-4-ylacetamide::N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(morpholin-4-yl)acetamide

SMILES: CCOc1nc(NC(=O)CN2CCOCC2)cc(N)c1C#N

InChI Key: InChIKey=XGCPEICJICGVBY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM15950 (Aminopyridine-Based Inhibitor 30 | N-(4-Amino-5-cy...) Show SMILES CCOc1nc(NC(=O)CN2CCOCC2)cc(N)c1C#N Show InChI InChI=1S/C14H19N5O3/c1-2-22-14-10(8-15)11(16)7-12(18-14)17-13(20)9-19-3-5-21-6-4-19/h7H,2-6,9H2,1H3,(H3,16,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 3563-80 (2006) Article DOI: 10.1021/jm060199b BindingDB Entry DOI: 10.7270/Q2P26WDX
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM15950 (Aminopyridine-Based Inhibitor 30 | N-(4-Amino-5-cy...) Show SMILES CCOc1nc(NC(=O)CN2CCOCC2)cc(N)c1C#N Show InChI InChI=1S/C14H19N5O3/c1-2-22-14-10(8-15)11(16)7-12(18-14)17-13(20)9-19-3-5-21-6-4-19/h7H,2-6,9H2,1H3,(H3,16,17,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 3563-80 (2006) Article DOI: 10.1021/jm060199b BindingDB Entry DOI: 10.7270/Q2P26WDX
					More data for this Ligand-Target Pair