BDBM163069 US9062004, 36::US9670216, 36 1-(2-Morpholin-4-ylethyl)-5-(3,3,5,5-tetramethylcyclohexyl)pyrazolo[3,4-d]pyridazin-4-one

SMILES: CC1(C)CC(CC(C)(C)C1)n1ncc2n(CCN3CCOCC3)ncc2c1=O

InChI Key: InChIKey=ZDVSUHLCUSNROB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 163069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM163069 (US9062004, 36 | US9670216, 36 1-(2-Morpholin-4-yle...) Show SMILES CC1(C)CC(CC(C)(C)C1)n1ncc2n(CCN3CCOCC3)ncc2c1=O Show InChI InChI=1S/C21H33N5O2/c1-20(2)11-16(12-21(3,4)15-20)26-19(27)17-13-22-25(18(17)14-23-26)6-5-24-7-9-28-10-8-24/h13-14,16H,5-12,15H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	219	n/a	n/a	n/a	n/a	n/a	n/a
Allergan, Inc. US Patent					Assay Description Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...				US Patent US9062004 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64SM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM163069 (US9062004, 36 | US9670216, 36 1-(2-Morpholin-4-yle...) Show SMILES CC1(C)CC(CC(C)(C)C1)n1ncc2n(CCN3CCOCC3)ncc2c1=O Show InChI InChI=1S/C21H33N5O2/c1-20(2)11-16(12-21(3,4)15-20)26-19(27)17-13-22-25(18(17)14-23-26)6-5-24-7-9-28-10-8-24/h13-14,16H,5-12,15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	25
ALLERGAN, INC. US Patent					Assay Description Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...				US Patent US9670216 (2017) BindingDB Entry DOI: 10.7270/Q2V98674
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM163069 (US9062004, 36 | US9670216, 36 1-(2-Morpholin-4-yle...) Show SMILES CC1(C)CC(CC(C)(C)C1)n1ncc2n(CCN3CCOCC3)ncc2c1=O Show InChI InChI=1S/C21H33N5O2/c1-20(2)11-16(12-21(3,4)15-20)26-19(27)17-13-22-25(18(17)14-23-26)6-5-24-7-9-28-10-8-24/h13-14,16H,5-12,15H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	219	n/a	n/a	n/a	n/a	n/a	25
ALLERGAN, INC. US Patent					Assay Description Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 pmol/mg protein, receptor conce...				US Patent US9670216 (2017) BindingDB Entry DOI: 10.7270/Q2V98674
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM163069 (US9062004, 36 | US9670216, 36 1-(2-Morpholin-4-yle...) Show SMILES CC1(C)CC(CC(C)(C)C1)n1ncc2n(CCN3CCOCC3)ncc2c1=O Show InChI InChI=1S/C21H33N5O2/c1-20(2)11-16(12-21(3,4)15-20)26-19(27)17-13-22-25(18(17)14-23-26)6-5-24-7-9-28-10-8-24/h13-14,16H,5-12,15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Allergan, Inc. US Patent					Assay Description Plasma membranes prepared from HEK 293 EBNA cells transfected with human CB1 or CB2 cannabinoid receptors (3.7 or 3.3 .mu.mol/mg protein, receptor co...				US Patent US9062004 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64SM
					More data for this Ligand-Target Pair