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SMILES: CN(CCOc1ccc2CCC(N)C(Cc3ccc(Cl)cc3)c2c1)S(=O)(=O)CC1CC1

InChI Key: InChIKey=BZFCKIDOAYCLFO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164651   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM164651
PNG
(US9067871, 129)
Show SMILES CN(CCOc1ccc2CCC(N)C(Cc3ccc(Cl)cc3)c2c1)S(=O)(=O)CC1CC1
Show InChI InChI=1S/C24H31ClN2O3S/c1-27(31(28,29)16-18-2-3-18)12-13-30-21-10-6-19-7-11-24(26)23(22(19)15-21)14-17-4-8-20(25)9-5-17/h4-6,8-10,15,18,23-24H,2-3,7,11-14,16,26H2,1H3
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Similars
US Patent
<10n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...

US Patent US9067871 (2015)


BindingDB Entry DOI: 10.7270/Q2HH6HV4
More data for this
Ligand-Target Pair