BDBM165062 US9067917, 97::US9682971, 97
SMILES: CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1
InChI Key: InChIKey=DJJUFJBCYHTNRA-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-lipoxygenase/FLAP (Homo sapiens (Human)) | BDBM165062![]() (US9067917, 97 | US9682971, 97) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV US Patent | Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... | US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-lipoxygenase/FLAP (Homo sapiens (Human)) | BDBM165062![]() (US9067917, 97 | US9682971, 97) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... | US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5 | |||||||||||
More data for this Ligand-Target Pair |