BDBM165174 US9067917, 209::US9067917, 210::US9682971, 210

SMILES: OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1

InChI Key: InChIKey=PKOYWFOHHRGCON-FCHUYYIVSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 165174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165174 (US9067917, 209 | US9067917, 210 | US9682971, 210) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C29H26BrN3O3S/c30-19-11-9-18(10-12-19)16-33-25-14-13-20(36-17-27-31-23-7-3-4-8-26(23)37-27)15-24(25)32-28(33)21-5-1-2-6-22(21)29(34)35/h3-4,7-15,21-22H,1-2,5-6,16-17H2,(H,34,35)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165174 (US9067917, 209 | US9067917, 210 | US9682971, 210) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C29H26BrN3O3S/c30-19-11-9-18(10-12-19)16-33-25-14-13-20(36-17-27-31-23-7-3-4-8-26(23)37-27)15-24(25)32-28(33)21-5-1-2-6-22(21)29(34)35/h3-4,7-15,21-22H,1-2,5-6,16-17H2,(H,34,35)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165174 (US9067917, 209 | US9067917, 210 | US9682971, 210) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C29H26BrN3O3S/c30-19-11-9-18(10-12-19)16-33-25-14-13-20(36-17-27-31-23-7-3-4-8-26(23)37-27)15-24(25)32-28(33)21-5-1-2-6-22(21)29(34)35/h3-4,7-15,21-22H,1-2,5-6,16-17H2,(H,34,35)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165174 (US9067917, 209 | US9067917, 210 | US9682971, 210) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C29H26BrN3O3S/c30-19-11-9-18(10-12-19)16-33-25-14-13-20(36-17-27-31-23-7-3-4-8-26(23)37-27)15-24(25)32-28(33)21-5-1-2-6-22(21)29(34)35/h3-4,7-15,21-22H,1-2,5-6,16-17H2,(H,34,35)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair