BDBM165399 US9062043, Table 13, Compound 67::US9062043, Table 20b, Compound 31
SMILES: Nc1ncc2c3ccc(cc3nc(Nc3ccc(F)c(Cl)c3)c2n1)C(O)=O
InChI Key: InChIKey=DXIOENHPVMRFQA-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM165399 (US9062043, Table 13, Compound 67 | US9062043, Tabl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.2 | n/a |
SENHWA BIOSCIENCES, INC. US Patent | Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A... | US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM165399 (US9062043, Table 13, Compound 67 | US9062043, Tabl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 44 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SENHWA BIOSCIENCES, INC. US Patent | Assay Description The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr... | US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF | |||||||||||
More data for this Ligand-Target Pair |