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SMILES: Cc1c(F)ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccc(F)cn2)c1Cl

InChI Key: InChIKey=DJBAQMUPYMOLTC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165812   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM165812
PNG
(US9067922, 147)
Show SMILES Cc1c(F)ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccc(F)cn2)c1Cl
Show InChI InChI=1S/C19H12ClF2N3O3S/c1-11-15(22)4-6-17(19(11)20)28-16-5-3-14(8-12(16)9-23)29(26,27)25-18-7-2-13(21)10-24-18/h2-8,10H,1H3,(H,24,25)
KEGG

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Similars
US Patent
n/an/a 187n/an/an/an/a7.4n/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...

US Patent US9067922 (2015)


BindingDB Entry DOI: 10.7270/Q2VQ31F0
More data for this
Ligand-Target Pair