BDBM166188 US9067949, 45

SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)c1cc(Cl)c2oc3CCNCc3c2c1

InChI Key: InChIKey=SVWPLMYJLBZCON-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM166188 (US9067949, 45) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cc(Cl)c2oc3CCNCc3c2c1 Show InChI InChI=1S/C18H13ClF3NO3S/c19-15-8-12(7-13-14-9-23-5-4-16(14)26-17(13)15)27(24,25)11-3-1-2-10(6-11)18(20,21)22/h1-3,6-8,23H,4-5,9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.480	-12.7	n/a	n/a	n/a	n/a	n/a	7.5	25
Albany Molecular Research, Inc. US Patent					Assay Description For binding analysis vs. the human receptor, samples were incubated in 50 mM Tris-HCl, pH 7.5, 5 mM MgCl2, 1 mM EDTA (4% DMSO final) with 10 nM [N-me...				US Patent US9067949 (2015) BindingDB Entry DOI: 10.7270/Q23777FB
					More data for this Ligand-Target Pair