BDBM166478 US9073853, 37
SMILES: COc1cc(CN(C[C@H]2CC[C@@H](CC2)C(O)=O)[C@@H](C)c2ccc(Cl)cc2)ccc1OCCn1c(=O)ccn(C)c1=O
InChI Key: InChIKey=OITFMGVRVSIALP-HWBMXIPRSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human)) | BDBM166478 (US9073853, 37) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Co. Ltd Curated by ChEMBL | Assay Description Displacement of [125I]-CXCL10 from human recombinant CXCR3 transfected in Flp-In-CHO cell membranes after 60 mins by gamma counting method | Bioorg Med Chem Lett 26: 5418-5428 (2016) Article DOI: 10.1016/j.bmcl.2016.10.035 BindingDB Entry DOI: 10.7270/Q28S4RW9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human)) | BDBM166478 (US9073853, 37) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description Competition radioligand binding assays were performed to determine the in vitro potency of the newly synthesized, unlabeled test compounds to displac... | US Patent US9073853 (2015) BindingDB Entry DOI: 10.7270/Q2Q23Z10 | |||||||||||
More data for this Ligand-Target Pair |