BDBM167465 US9073911, 14
SMILES: Clc1ccc(cc1)-c1cc([nH]n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1
InChI Key:
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse)) | BDBM167465 (US9073911, 14) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ... | US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat)) | BDBM167465 (US9073911, 14) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ... | US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX | |||||||||||
More data for this Ligand-Target Pair |