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SMILES: C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnc2ccccc2c1

InChI Key: InChIKey=GNBSFKOHIIYQLM-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168030   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))		BDBM168030
PNG
(US9073926, 64)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnc2ccccc2c1 |r|
Show InChI InChI=1S/C21H17N5O2/c1-12-10-23-21(28)18-9-14-6-7-17(25-19(14)26(12)18)20(27)24-15-8-13-4-2-3-5-16(13)22-11-15/h2-9,11-12H,10H2,1H3,(H,23,28)(H,24,27)/t12-/m1/s1
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Similars
US Patent
n/an/a 3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...

US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair