null

SMILES: CC1(C)CCCC11NC(=O)c2ccc(Nc3ccncn3)c(=O)n12

InChI Key: InChIKey=VEEXATBXYUTWTO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168205 (US9669031, 36 2′,2′-dimethyl-6-(pyrimi...) Show SMILES CC1(C)CCCC11NC(=O)c2ccc(Nc3ccncn3)c(=O)n12 Show InChI InChI=1S/C17H19N5O2/c1-16(2)7-3-8-17(16)21-14(23)12-5-4-11(15(24)22(12)17)20-13-6-9-18-10-19-13/h4-6,9-10H,3,7-8H2,1-2H3,(H,21,23)(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM168205 (US9669031, 36 2′,2′-dimethyl-6-(pyrimi...) Show SMILES CC1(C)CCCC11NC(=O)c2ccc(Nc3ccncn3)c(=O)n12 Show InChI InChI=1S/C17H19N5O2/c1-16(2)7-3-8-17(16)21-14(23)12-5-4-11(15(24)22(12)17)20-13-6-9-18-10-19-13/h4-6,9-10H,3,7-8H2,1-2H3,(H,21,23)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
					More data for this Ligand-Target Pair