BDBM168431 US9675571, 87

SMILES: OC(=O)[C@@H]1C[C@@H]1c1ccc(N(CCC(F)(F)F)C2CCCCC2)c(NC(=O)Nc2cncnc2)c1

InChI Key: InChIKey=KFQMVKMYOAUEQO-RTBURBONSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM168431 (US9675571, 87) Show SMILES OC(=O)[C@@H]1C[C@@H]1c1ccc(N(CCC(F)(F)F)C2CCCCC2)c(NC(=O)Nc2cncnc2)c1 |r| Show InChI InChI=1S/C24H28F3N5O3/c25-24(26,27)8-9-32(17-4-2-1-3-5-17)21-7-6-15(18-11-19(18)22(33)34)10-20(21)31-23(35)30-16-12-28-14-29-13-16/h6-7,10,12-14,17-19H,1-5,8-9,11H2,(H,33,34)(H2,30,31,35)/t18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	994	n/a	n/a	n/a	25
SRMLSC US Patent					Assay Description Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...				US Patent US9675571 (2017) BindingDB Entry DOI: 10.7270/Q2BK19HD
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