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SMILES: Cc1cc(=O)n(cc1-c1cnn(C)c1)-c1cccc(NC(N)=O)c1

InChI Key: InChIKey=IPWRKBKVEUOLBD-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172576   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1


(Homo sapiens (Human))		BDBM172576
PNG
(US9675593, 628)
Show SMILES Cc1cc(=O)n(cc1-c1cnn(C)c1)-c1cccc(NC(N)=O)c1
Show InChI InChI=1S/C17H17N5O2/c1-11-6-16(23)22(10-15(11)12-8-19-21(2)9-12)14-5-3-4-13(7-14)20-17(18)24/h3-10H,1-2H3,(H3,18,20,24)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<5.00E+4n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...

US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair