BDBM172638 US9090628, 298

SMILES: CC(C)n1nc(N)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1ccnn1C1CCN(C)CC1

InChI Key: InChIKey=DABMYKAIKAZERR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172638 (US9090628, 298) Show SMILES CC(C)n1nc(N)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1ccnn1C1CCN(C)CC1 Show InChI InChI=1S/C25H31N9O/c1-16(2)33-24(29-25(26)30-33)20-15-32-12-13-35-22-14-17(4-5-19(22)23(32)28-20)21-6-9-27-34(21)18-7-10-31(3)11-8-18/h4-6,9,14-16,18H,7-8,10-13H2,1-3H3,(H2,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.705	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair