BDBM174733 US9102670, 19g

SMILES: COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)-c1cc(cc(c1)[N+]([O-])=O)C(O)=O)N1CCOC[C@@H]1C

InChI Key: InChIKey=YXXNZRADJBNILP-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM174733 (US9102670, 19g) Show SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)-c1cc(cc(c1)[N+]([O-])=O)C(O)=O)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C27H25N5O7/c1-15-14-39-8-7-31(15)26-21-4-5-22(16-3-6-23(38-2)19(9-16)13-33)28-25(21)29-24(30-26)17-10-18(27(34)35)12-20(11-17)32(36)37/h3-6,9-12,15,33H,7-8,13-14H2,1-2H3,(H,34,35)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	25
KUDOS PHARMACEUTICALS LIMITED US Patent					Assay Description The assay used AlphaScreen technology (Gray et al., Analytical Biochemistry, 2003, 313: 234-245) to determine the ability of test compounds to inhibi...				US Patent US9102670 (2015) BindingDB Entry DOI: 10.7270/Q26M35MZ
					More data for this Ligand-Target Pair