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SMILES: Cc1cn(cn1)-c1ccc(nn1)N1CCC(CC1)c1noc2ccc(F)cc12

InChI Key: InChIKey=YNJJNKJRNAZYAT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174893   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Rattus norvegicus (Rat))		BDBM174893
PNG
(US9102669, 85)
Show SMILES Cc1cn(cn1)-c1ccc(nn1)N1CCC(CC1)c1noc2ccc(F)cc12
Show InChI InChI=1S/C20H19FN6O/c1-13-11-27(12-22-13)19-5-4-18(23-24-19)26-8-6-14(7-9-26)20-16-10-15(21)2-3-17(16)28-25-20/h2-5,10-12,14H,6-9H2,1H3
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Similars
US Patent
n/an/a 65n/an/an/an/an/a25



Janssen Pharmaceutica NV

US Patent


Assay Description
The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...

US Patent US9102669 (2015)


BindingDB Entry DOI: 10.7270/Q2BC3X9V
More data for this
Ligand-Target Pair