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SMILES: NNC(=O)c1ccc(nn1)N1CCC(CC1)c1noc2ccc(F)cc12

InChI Key: InChIKey=NUUGCYKZMHJWGB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174906   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Rattus norvegicus (Rat))		BDBM174906
PNG
(US9102669, I1)
Show SMILES NNC(=O)c1ccc(nn1)N1CCC(CC1)c1noc2ccc(F)cc12
Show InChI InChI=1S/C17H17FN6O2/c18-11-1-3-14-12(9-11)16(23-26-14)10-5-7-24(8-6-10)15-4-2-13(21-22-15)17(25)20-19/h1-4,9-10H,5-8,19H2,(H,20,25)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 59n/an/an/an/an/a25



Janssen Pharmaceutica NV

US Patent


Assay Description
The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...

US Patent US9102669 (2015)


BindingDB Entry DOI: 10.7270/Q2BC3X9V
More data for this
Ligand-Target Pair