BDBM175533 US9120744, CDE-011

SMILES: Oc1cc(cc(O)c1O)C(=O)OCCOCCOCCOCCOC(=O)c1cc(O)c(O)c(O)c1

InChI Key: InChIKey=AJLPSWGUSHMDMC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM175533 (US9120744, CDE-011) Show SMILES Oc1cc(cc(O)c1O)C(=O)OCCOCCOCCOCCOC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C22H26O13/c23-15-9-13(10-16(24)19(15)27)21(29)34-7-5-32-3-1-31-2-4-33-6-8-35-22(30)14-11-17(25)20(28)18(26)12-14/h9-12,23-28H,1-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.38E+5	n/a	n/a	n/a	n/a	7.8	23
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...				US Patent US9120744 (2015) BindingDB Entry DOI: 10.7270/Q2QF8RN8
					More data for this Ligand-Target Pair