BDBM176578 US9120756, 126

SMILES: Fc1cc(NC(=O)NCc2cc(nn2-c2cccc(Cl)c2)C(F)(F)F)ccc1C1CC1

InChI Key: InChIKey=KPCZXNHTLREUJC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176578 (US9120756, 126) Show SMILES Fc1cc(NC(=O)NCc2cc(nn2-c2cccc(Cl)c2)C(F)(F)F)ccc1C1CC1 Show InChI InChI=1S/C21H17ClF4N4O/c22-13-2-1-3-15(8-13)30-16(10-19(29-30)21(24,25)26)11-27-20(31)28-14-6-7-17(12-4-5-12)18(23)9-14/h1-3,6-10,12H,4-5,11H2,(H2,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	31.4	-10.6	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair