null

SMILES: CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)CCOCC3)c(=O)c2=O)c1O

InChI Key: InChIKey=ZMIYRIGYJBURQV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM177694 (US9120772, 6) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)CCOCC3)c(=O)c2=O)c1O Show InChI InChI=1S/C25H29N3O6/c1-14-8-9-17(34-14)23(25(2)10-12-33-13-11-25)27-19-18(21(30)22(19)31)26-16-7-5-6-15(20(16)29)24(32)28(3)4/h5-9,23,26-27,29H,10-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the beta -ar...				US Patent US9120772 (2015) BindingDB Entry DOI: 10.7270/Q2PG1QHF
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM177694 (US9120772, 6) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)CCOCC3)c(=O)c2=O)c1O Show InChI InChI=1S/C25H29N3O6/c1-14-8-9-17(34-14)23(25(2)10-12-33-13-11-25)27-19-18(21(30)22(19)31)26-16-7-5-6-15(20(16)29)24(32)28(3)4/h5-9,23,26-27,29H,10-13H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the beta -ar...				US Patent US9120772 (2015) BindingDB Entry DOI: 10.7270/Q2PG1QHF
					More data for this Ligand-Target Pair