BDBM177774 US10000475, Compound 3::US9120786, 3
SMILES: FC(F)(F)c1ccc(Oc2ccc(cc2)-c2nc(N[C@H]3CCNC3=O)nc(n2)C#N)nc1
InChI Key: InChIKey=FCPYRLPAPSYZRM-AWEZNQCLSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM177774 (US10000475, Compound 3 | US9120786, 3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite degli Studi di Firenze | Assay Description The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th... | Bioorg Med Chem 17: 4503-9 (2009) BindingDB Entry DOI: 10.7270/Q20004F3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM177774 (US10000475, Compound 3 | US9120786, 3) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
Purdue Pharma, L.P. US Patent | Assay Description FLIPRTETRA Sodium Dye Assay with KCl: Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant o... | US Patent US9120786 (2015) BindingDB Entry DOI: 10.7270/Q25D8QKN | |||||||||||
More data for this Ligand-Target Pair |