BDBM178056 1,2,4-tribromo-3-{[2-(2,5-dibromo-3,4-dimethoxyphenyl)cyclopentyl]methyl}-5,6-dimethoxybenzene (20)
SMILES: COc1c(Br)cc(C2CCCC2Cc2c(Br)c(Br)c(OC)c(OC)c2Br)c(Br)c1OC
InChI Key: InChIKey=BLVBNJFNNIXSHF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM178056 (1,2,4-tribromo-3-{[2-(2,5-dibromo-3,4-dimethoxyphe...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 313 | n/a | 275 | n/a | n/a | n/a | n/a | n/a | n/a |
Atat£rk University | Assay Description CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ... | Chem Biol Drug Des 87: 594-607 (2016) Article DOI: 10.1111/cbdd.12695 BindingDB Entry DOI: 10.7270/Q20R9N5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM178056 (1,2,4-tribromo-3-{[2-(2,5-dibromo-3,4-dimethoxyphe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 510 | n/a | 475 | n/a | n/a | n/a | n/a | n/a | n/a |
Atat£rk University | Assay Description CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ... | Chem Biol Drug Des 87: 594-607 (2016) Article DOI: 10.1111/cbdd.12695 BindingDB Entry DOI: 10.7270/Q20R9N5Q | |||||||||||
More data for this Ligand-Target Pair |