BDBM178133 3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-1,2-diol (3)

SMILES: Oc1cccc(-c2nc3ncc(Cl)cc3[nH]2)c1O

InChI Key: InChIKey=YQRZXSVHKFALLX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 178133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-glucuronidase (β-glucuronidase) (Bos taurus (Bovine))	BDBM178133 (3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) Show SMILES Oc1cccc(-c2nc3ncc(Cl)cc3[nH]2)c1O Show InChI InChI=1S/C12H8ClN3O2/c13-6-4-8-12(14-5-6)16-11(15-8)7-2-1-3-9(17)10(7)18/h1-5,17-18H,(H,14,15,16)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA (UiTM), Puncak Alam Campus					Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o...				Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X
					More data for this Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM178133 (3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) Show SMILES Oc1cccc(-c2nc3ncc(Cl)cc3[nH]2)c1O Show InChI InChI=1S/C12H8ClN3O2/c13-6-4-8-12(14-5-6)16-11(15-8)7-2-1-3-9(17)10(7)18/h1-5,17-18H,(H,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020)
					More data for this Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM178133 (3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) Show SMILES Oc1cccc(-c2nc3ncc(Cl)cc3[nH]2)c1O Show InChI InChI=1S/C12H8ClN3O2/c13-6-4-8-12(14-5-6)16-11(15-8)7-2-1-3-9(17)10(7)18/h1-5,17-18H,(H,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan University of Technology Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate...				Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063
					More data for this Ligand-Target Pair