BDBM17869 (3S)-3-amino-1-(cyclopropylamino)heptane-2,2-diol::aminoketone inhibitor, 3

SMILES: CCCC[C@H](N)C(=O)CNC1CC1

InChI Key: InChIKey=RRBXQUJIDMTEET-VIFPVBQESA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (Staphylococcus aureus)	BDBM17869 ((3S)-3-amino-1-(cyclopropylamino)heptane-2,2-diol ...) Show SMILES CCCC[C@H](N)C(=O)CNC1CC1 |r| Show InChI InChI=1S/C10H20N2O/c1-2-3-4-9(11)10(13)7-12-8-5-6-8/h8-9,12H,2-7,11H2,1H3/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	7.5	22
Morphochem AG					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				J Med Chem 47: 1325-8 (2004) Article DOI: 10.1021/jm034188j BindingDB Entry DOI: 10.7270/Q2GX48TV
					More data for this Ligand-Target Pair				3D Structure (crystal)