BDBM179580 US9126980, 25

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(NC(C)=O)c(Cl)c2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=DANWOBJWEFZVQD-HDYGDMNUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179580 (US9126980, 25) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(NC(C)=O)c(Cl)c2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C38H45ClN6O5S/c1-5-7-17-43(18-8-6-2)38(49)35-19-25(3)45(41-35)36-16-13-29(42-51(50)31-14-15-34(33(39)22-31)40-26(4)47)21-32(36)37(48)44-23-28-12-10-9-11-27(28)20-30(44)24-46/h9-16,19,21-22,30,42,46H,5-8,17-18,20,23-24H2,1-4H3,(H,40,47)/t30-,51?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	255	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179580 (US9126980, 25) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(NC(C)=O)c(Cl)c2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C38H45ClN6O5S/c1-5-7-17-43(18-8-6-2)38(49)35-19-25(3)45(41-35)36-16-13-29(42-51(50)31-14-15-34(33(39)22-31)40-26(4)47)21-32(36)37(48)44-23-28-12-10-9-11-27(28)20-30(44)24-46/h9-16,19,21-22,30,42,46H,5-8,17-18,20,23-24H2,1-4H3,(H,40,47)/t30-,51?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair