BDBM181815 US9145380, 18

SMILES: NS(=O)(=O)c1ccccc1NS(=O)(=O)\C=C\c1ccc(cc1)-c1ccco1

InChI Key: InChIKey=NDGUTZUJOOVPOQ-ACCUITESSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase 2 (Homo sapiens (Human))	BDBM181815 (US9145380, 18) Show SMILES NS(=O)(=O)c1ccccc1NS(=O)(=O)\C=C\c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C18H16N2O5S2/c19-27(23,24)18-6-2-1-4-16(18)20-26(21,22)13-11-14-7-9-15(10-8-14)17-5-3-12-25-17/h1-13,20H,(H2,19,23,24)/b13-11+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	6.8	n/a
Astrazeneca AB US Patent					Assay Description A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...				US Patent US9145380 (2015) BindingDB Entry DOI: 10.7270/Q2XG9PXM
					More data for this Ligand-Target Pair