null

SMILES: COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=UDKRZHKBWBJIRH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 183110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183110 (US9150546, I-248 | US9688643, I-248 | US9718790, I...) Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H21ClN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183110 (US9150546, I-248 | US9688643, I-248 | US9718790, I...) Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H21ClN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183110 (US9150546, I-248 | US9688643, I-248 | US9718790, I...) Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H21ClN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183110 (US9150546, I-248 | US9688643, I-248 | US9718790, I...) Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H21ClN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair