BDBM183397 US9145419, 7

SMILES: Cc1ccncc1-c1ccnn2c(cnc12)-c1ccc(F)cc1

InChI Key: InChIKey=ACEGOQOUKHTDCR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM183397 (US9145419, 7) Show SMILES Cc1ccncc1-c1ccnn2c(cnc12)-c1ccc(F)cc1 Show InChI InChI=1S/C18H13FN4/c1-12-6-8-20-10-16(12)15-7-9-22-23-17(11-21-18(15)23)13-2-4-14(19)5-3-13/h2-11H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.2	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...				US Patent US9145419 (2015) BindingDB Entry DOI: 10.7270/Q208643N
					More data for this Ligand-Target Pair