BDBM183662 US9150519, 1-42

SMILES: COCCNS(=O)(=O)c1ccc(NC(=O)c2cc(ncn2)N(C)C2CCCCC2)cc1

InChI Key: InChIKey=HWJJFNFLAHEPFE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM183662 (US9150519, 1-42) Show SMILES COCCNS(=O)(=O)c1ccc(NC(=O)c2cc(ncn2)N(C)C2CCCCC2)cc1 Show InChI InChI=1S/C21H29N5O4S/c1-26(17-6-4-3-5-7-17)20-14-19(22-15-23-20)21(27)25-16-8-10-18(11-9-16)31(28,29)24-12-13-30-2/h8-11,14-15,17,24H,3-7,12-13H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2.28E+3	n/a	n/a	7.4	30
MERCK SERONO SA US Patent					Assay Description Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...				US Patent US9150519 (2015) BindingDB Entry DOI: 10.7270/Q2H993ZK
					More data for this Ligand-Target Pair