BDBM183824 US9150526, 77

SMILES: COc1ccc(CO)cc1-c1cc(Cl)cc(c1)C(CC(O)=O)c1ncc(C)s1

InChI Key: InChIKey=LIAXUEDJGRBKIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin A (CTSA) (Homo sapiens (Human))	BDBM183824 (US9150526, 77) Show SMILES COc1ccc(CO)cc1-c1cc(Cl)cc(c1)C(CC(O)=O)c1ncc(C)s1 Show InChI InChI=1S/C21H20ClNO4S/c1-12-10-23-21(28-12)18(9-20(25)26)15-6-14(7-16(22)8-15)17-5-13(11-24)3-4-19(17)27-2/h3-8,10,18,24H,9,11H2,1-2H3,(H,25,26)	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	6.0	37
Sanofi US Patent					Assay Description Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h...				US Patent US9150526 (2015) BindingDB Entry DOI: 10.7270/Q2QR4VXP
					More data for this Ligand-Target Pair