BDBM185701 US9161939, 2::US9271981, 2
SMILES: CN([C@H]1CC[C@H](CS(=O)(=O)NC2CCC2)CC1)c1ncnc2[nH]ccc12
InChI Key:
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM185701 (US9161939, 2 | US9271981, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9161939 (2015) BindingDB Entry DOI: 10.7270/Q2CC0ZF7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM185701 (US9161939, 2 | US9271981, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 101 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9161939 (2015) BindingDB Entry DOI: 10.7270/Q2CC0ZF7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 [781-1124] (Homo sapiens (Human)) | BDBM185701 (US9161939, 2 | US9271981, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 742 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9271981 (2016) BindingDB Entry DOI: 10.7270/Q2VD6X90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 [852-1142] (Homo sapiens (Human)) | BDBM185701 (US9161939, 2 | US9271981, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9271981 (2016) BindingDB Entry DOI: 10.7270/Q2VD6X90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 [809-1153] (Homo sapiens (Human)) | BDBM185701 (US9161939, 2 | US9271981, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 101 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9271981 (2016) BindingDB Entry DOI: 10.7270/Q2VD6X90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM185701 (US9161939, 2 | US9271981, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 742 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Zoetis Services LLC US Patent | Assay Description Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk... | US Patent US9161939 (2015) BindingDB Entry DOI: 10.7270/Q2CC0ZF7 | |||||||||||
More data for this Ligand-Target Pair |