null

SMILES: COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(Cc2nc3ccccc(=O)c3[nH]2)C1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM185815 (US9163003, 27) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(Cc2nc3ccccc(=O)c3[nH]2)C1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM185815 (US9163003, 27) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(Cc2nc3ccccc(=O)c3[nH]2)C1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6
					More data for this Ligand-Target Pair