BDBM185857 US9163007, 197

SMILES: NC1CCN(CC1)C(=O)c1c(nnn1Cc1ccccc1)-c1ccc2[nH]ncc2c1

InChI Key: InChIKey=WQBNSUXFVJXQCA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM185857 (US9163007, 197) Show SMILES NC1CCN(CC1)C(=O)c1c(nnn1Cc1ccccc1)-c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C22H23N7O/c23-18-8-10-28(11-9-18)22(30)21-20(16-6-7-19-17(12-16)13-24-25-19)26-27-29(21)14-15-4-2-1-3-5-15/h1-7,12-13,18H,8-11,14,23H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description 6 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 us...				US Patent US9163007 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DTG
					More data for this Ligand-Target Pair