BDBM185956 US9163008, 45::US9656968, Compound 45

SMILES: NC(=O)c1cc(NCC2(O)CCCCC2)nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key: InChIKey=YDTDFPARVOEQMG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185956 (US9163008, 45 | US9656968, Compound 45) Show SMILES NC(=O)c1cc(NCC2(O)CCCCC2)nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C24H25FN4O3/c25-17-6-10-19(11-7-17)32-18-8-4-16(5-9-18)23-28-20(22(26)30)14-21(29-23)27-15-24(31)12-2-1-3-13-24/h4-11,14,31H,1-3,12-13,15H2,(H2,26,30)(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...				US Patent US9656968 (2017) BindingDB Entry DOI: 10.7270/Q2F76FMS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185956 (US9163008, 45 | US9656968, Compound 45) Show SMILES NC(=O)c1cc(NCC2(O)CCCCC2)nc(n1)-c1ccc(Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C24H25FN4O3/c25-17-6-10-19(11-7-17)32-18-8-4-16(5-9-18)23-28-20(22(26)30)14-21(29-23)27-15-24(31)12-2-1-3-13-24/h4-11,14,31H,1-3,12-13,15H2,(H2,26,30)(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair