BDBM190891 US10077266, Example 2::US9181249, 2::US9708313, 2

SMILES: COCC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC(C)C)nc2C1

InChI Key: InChIKey=WIDYNDYFLUIBHH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190891 (US10077266, Example 2 | US9181249, 2 | US9708313, ...) Show SMILES COCC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC(C)C)nc2C1 Show InChI InChI=1S/C24H31F2N5O3/c1-15(2)27-23-24(29-19-8-11-31(13-20(19)28-23)22(32)14-33-3)30-9-6-17(7-10-30)34-21-5-4-16(25)12-18(21)26/h4-5,12,15,17H,6-11,13-14H2,1-3H3,(H,27,28)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0715	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9181249 (2015) BindingDB Entry DOI: 10.7270/Q2HM577D
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190891 (US10077266, Example 2 | US9181249, 2 | US9708313, ...) Show SMILES COCC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC(C)C)nc2C1 Show InChI InChI=1S/C24H31F2N5O3/c1-15(2)27-23-24(29-19-8-11-31(13-20(19)28-23)22(32)14-33-3)30-9-6-17(7-10-30)34-21-5-4-16(25)12-18(21)26/h4-5,12,15,17H,6-11,13-14H2,1-3H3,(H,27,28)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9708313 (2017) BindingDB Entry DOI: 10.7270/Q2ZP4858
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190891 (US10077266, Example 2 | US9181249, 2 | US9708313, ...) Show SMILES COCC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC(C)C)nc2C1 Show InChI InChI=1S/C24H31F2N5O3/c1-15(2)27-23-24(29-19-8-11-31(13-20(19)28-23)22(32)14-33-3)30-9-6-17(7-10-30)34-21-5-4-16(25)12-18(21)26/h4-5,12,15,17H,6-11,13-14H2,1-3H3,(H,27,28)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US10077266 (2018) BindingDB Entry DOI: 10.7270/Q2T155PB
					More data for this Ligand-Target Pair