null

SMILES: O[C@@H](Cn1c(nn(Cc2nnc(s2)-c2ccccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=GRJNKBDCMVJZIA-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM192447 (US9187466, 20 | US9687476, 20) Show SMILES O[C@@H](Cn1c(nn(Cc2nnc(s2)-c2ccccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H14ClF6N5O2S/c22-12-7-5-11(6-8-12)17-31-33(19(35)32(17)9-15(34)21(26,27)28)10-16-29-30-18(36-16)13-3-1-2-4-14(13)20(23,24)25/h1-8,15,34H,9-10H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9187466 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02MT
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM192447 (US9187466, 20 | US9687476, 20) Show SMILES O[C@@H](Cn1c(nn(Cc2nnc(s2)-c2ccccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H14ClF6N5O2S/c22-12-7-5-11(6-8-12)17-31-33(19(35)32(17)9-15(34)21(26,27)28)10-16-29-30-18(36-16)13-3-1-2-4-14(13)20(23,24)25/h1-8,15,34H,9-10H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	37
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9687476 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6QDG
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM192447 (US9187466, 20 | US9687476, 20) Show SMILES O[C@@H](Cn1c(nn(Cc2nnc(s2)-c2ccccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H14ClF6N5O2S/c22-12-7-5-11(6-8-12)17-31-33(19(35)32(17)9-15(34)21(26,27)28)10-16-29-30-18(36-16)13-3-1-2-4-14(13)20(23,24)25/h1-8,15,34H,9-10H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	37
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9687476 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6QDG
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM192447 (US9187466, 20 | US9687476, 20) Show SMILES O[C@@H](Cn1c(nn(Cc2nnc(s2)-c2ccccc2C(F)(F)F)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H14ClF6N5O2S/c22-12-7-5-11(6-8-12)17-31-33(19(35)32(17)9-15(34)21(26,27)28)10-16-29-30-18(36-16)13-3-1-2-4-14(13)20(23,24)25/h1-8,15,34H,9-10H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description On the day before the assay, the cells are plated out in culture medium (DMEM, 10% FCS, 2 mM glutamine, 10 mM HEPES) in 384-well microtiter plates an...				US Patent US9187466 (2015) BindingDB Entry DOI: 10.7270/Q2WQ02MT
					More data for this Ligand-Target Pair